Characterization of the Na+/H+ exchanger in human choriocarcinoma (BeWo) cells.

doi:10.1007/s004240050347

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Article

Characterization of the Na+/H+ exchanger in human choriocarcinoma (BeWo) cells.

Pflugers Archiv : European journal of physiology - 1 Apr 1997

Silva N L, Wang H, Harris C V, Singh D, Fliegel L

Abstract excerpt

We examined the expression and activity of the Na+/H+ exchanger in the human choriocarcinoma BeWo cell line. When treated with methotrexate, these cells differentiated from cytotrophoblast-like cells to enlarged multinucleate syncytiotrophoblast-like cells. There was no change in the apparent Km...

Topics

Blotting, Northern
Blotting, Western
Cell Differentiation
Cell Membrane
Choriocarcinoma
Humans
Hydrogen-Ion Concentration
Immunohistochemistry
Isomerism
Kinetics
Microscopy, Electron, Scanning
Phenotype
RNA
Sodium-Hydrogen Exchangers
Tumor Cells, Cultured

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Open in PubMed

Identifiers

PMID: 9049172
DOI: 10.1007/s004240050347

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9049172-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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