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Article

Cloning, localization, and functional expression of the electrogenic Na+ bicarbonate cotransporter (NBCe1) from zebrafish.

American journal of physiology. Cell physiology - 1 Oct 2009

Sussman Caroline R, Zhao Jinhua, Plata Consuelo, Lu Jing, Daly Christopher, Angle Nathan, DiPiero Jennifer, Drummond Iain A, Liang Jennifer O, Boron Walter F, Romero Michael F, Chang Min-Hwang

Abstract excerpt

Mutations in the electrogenic Na+/nHCO3- cotransporter (NBCe1, SLC4A4) cause severe proximal renal tubular acidosis, glaucoma, and cataracts in humans, indicating NBCe1 has a critical role in acid-base homeostasis and ocular fluid transport. To better understand the homeostatic roles and protein ontogeny of NBCe1, we have cloned, localized, and downregulated NBCe1 expression in zebrafish, and examined its...

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Identifiers

PMID: 19625604
DOI: 10.1152/ajpcell.00679.2008
PMCID: PMC2770747

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Cloning, localization, and functional expression of the electrogenic Na+ bicarbonate cotransporter (NBCe1) from zebrafish.PMID 19625604Read ↗

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