Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatitis C lipo-Viro-particle from chronically infected patients interferes with TLR4 signaling in dendritic cell.

PloS one - 28 Mar 2007

Agaugué Sophie, Perrin-Cocon Laure, André Patrice, Lotteau Vincent

Abstract excerpt

BACKGROUND: Hepatitis C virus (HCV) can be purified from serum of chronically-infected patients in the form of Lipo-Viro-Particles (LVP), which are triglycerid-rich lipoprotein-like particles containing viral RNA and proteins. Since LVP is a constant feature of chronically infected patients, we asked whether purified LVP could interfere with the immune response by acting directly on dendritic cell (DC) function....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dendritic Cells
Share to Hepatitis C, Chronic
Share to Lipoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphocyte Culture Test, Mixed

Share to Lymphocytes

Share to Monocytes

Share to Toll-Like Receptor 4

Share to Triglycerides

Source

Open in PubMed Open full text

Identifiers

PMID: 17389921
DOI: 10.1371/journal.pone.0000330
PMCID: PMC1828622

Genes

TLR4
TLR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatitis C lipo-Viro-particle from chronically infected patients interferes with TLR4 signaling in dendritic cell.PMID 17389921Read ↗

Monocyte-derived dendritic cells from chronic HCV patients are not infected but show an immature phenotype and aberrant cytokine profile.Semantic proximity Read ↗

Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection.Semantic proximity Read ↗

Analysis of peripheral blood dendritic cells as a non-invasive tool in the follow-up of patients with chronic hepatitis C.Semantic proximity Read ↗

Hepatitis C virus structural proteins do not prevent human dendritic cell maturation.Semantic proximity Read ↗

Hepatitis C Virus Is a Weak Inducer of Interferon Alpha in Plasmacytoid Dendritic Cells in Comparison with Influenza and Human Herpesvirus Type-1Semantic proximity Read ↗

Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection.Semantic proximity Read ↗

Infection and dysfunction of circulating blood dendritic cells and their subsets in chronic hepatitis C virus infection.Semantic proximity Read ↗

Phenotype and function of monocyte derived dendritic cells in chronic hepatitis B virus infection.Semantic proximity Read ↗

Generation of hepatitis C virus-specific cytotoxic T lymphocytes from healthy individuals with peptide-pulsed dendritic cells.Semantic proximity Read ↗

HBV and HBsAg strongly reshape the phenotype, function, and metabolism of DCs according to patients' clinical stage.Semantic proximity Read ↗

Human blood dendritic cell antigen 3 (BDCA3)(+) dendritic cells are a potent producer of interferon-λ in response to hepatitis C virus.Semantic proximity Read ↗

Generation and characterization of an immunogenic dendritic cell population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.