Article
Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection.
Hepatology (Baltimore, Md.) - 1 Dec 2012
Velazquez Victoria M, Hon Huiming, Ibegbu Chris, Knechtle Stuart J, Kirk Allan D, Grakoui Arash
Abstract excerpt
UNLABELLED: Chronic hepatitis C virus (HCV) infection is a serious disease that can result in numerous long-term complications leading to liver failure or death. Approximately 80% of people fail to clear their infection, largely as the result of weak, narrowly targeting or waning antiviral T-cell responses. Although professional antigen presenting cells (APCs) like dendritic cells (DCs) might serve as targets for...
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