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Article

HBV and HBsAg strongly reshape the phenotype, function, and metabolism of DCs according to patients' clinical stage.

Hepatology communications - 1 Feb 2025

Dumolard Lucile, Gerster Theophile, Chuffart Florent, Decaens Thomas, Hilleret Marie-Noelle, Larrat Sylvie, Saas Philippe, Jouvin-Marche Evelyne, Durantel David, Marche Patrice N, Macek Jilkova Zuzana, Aspord Caroline

Abstract excerpt

BACKGROUND: Hepatitis B is a liver infection caused by HBV. Infected individuals who fail to control the viral infection develop chronic hepatitis B and are at risk of developing life-threatening liver diseases, such as cirrhosis or liver cancer. Dendritic cells (DCs) play important roles in the immune response against HBV but are functionally impaired in patients with chronic hepatitis B. The underlying...

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Identifiers

PMID: 39878655
DOI: 10.1097/HC9.0000000000000625
PMCID: PMC11781764

Genes

CX3CL1
CX3CR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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