Article
Phenotype and function of monocyte derived dendritic cells in chronic hepatitis B virus infection.
The Journal of general virology - 1 Oct 2004
Tavakoli Soheila, Schwerin Wibke, Rohwer Andreas, Hoffmann Sina, Weyer Sandra, Weth Robert, Meisel Helga, Diepolder Helmut, Geissler Michael, Galle Peter R, Löhr Hanns F, Böcher Wulf O
Abstract excerpt
The antiviral T cell failure of patients with chronic hepatitis B virus (HBV) infection was suggested to be caused by a T cell stimulation defect of dendritic cells (DC). To address this hypothesis, monocyte derived DC (MDDC) of patients with chronic or resolved acute HBV infection and healthy controls were studied phenotypically by FACS analyses and functionally by mixed lymphocyte reaction, ELISA, ELISpot and...
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