Article
Infection and dysfunction of circulating blood dendritic cells and their subsets in chronic hepatitis C virus infection.
Journal of gastroenterology - 1 Aug 2004
Tsubouchi Eiji, Akbar Sk Md Fazle, Horiike Norio, Onji Morikazu
Abstract excerpt
BACKGROUND: To understand interactions between dendritic cells (DCs) and viruses, in vitro-cultured monocyte-derived DCs are usually used for functional analyses. However, several recent studies indicate that circulating blood DCs are different from monocyte-derived DCs, both phenotypically and functionally. Indeed, circulating DCs act as functional antigen-presenting cells in vivo. This study was conducted to...
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