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Article

Crohn's disease and SLC11A1 promoter polymorphism.

Digestive diseases and sciences - 1 Jul 2007

Chermesh Irit, Azriel Aviva, Alter-Koltunoff Michal, Eliakim Rami, Karban Amir, Levi Ben Zion

Abstract excerpt

Crohn's disease (CD) is a chronic multifactorial inflammatory disease. The prevalence of CD in Ashkenazi Jews is higher than in Sephardic Jews. SLC11A1, also known as Nramp1, is a divalent cation antiporter essential for the elimination of intraphagosomal pathogens. SLC11A1 has seven alleles in the promoter region and previous studies have suggested an association between CD and SLC11A1. The aim of this study was...

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Source

Identifiers

PMID: 17385031
DOI: 10.1007/s10620-006-9682-3

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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