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Article

Similarities and differences between the light and heavy chain Ig variable region gene repertoires in chronic lymphocytic leukemia.

Molecular medicine (Cambridge, Mass.) - 1 Jan 2000

Ghiotto Fabio, Fais Franco, Albesiano Emilia, Sison Cristina, Valetto Angelo, Gaidano Gianluca, Reinhardt Janine, Kolitz Jonathan E, Rai Kanti, Allen Steven L, Ferrarini Manlio, Chiorazzi Nicholas

Abstract excerpt

Analyses of Ig V(H)DJ(H) rearrangements expressed by B-CLL cells have provided insights into the antigen receptor repertoire of B-CLL cells and the maturation stages of B-lymphocytes that give rise to this disease. However, less information is available about the L chain V gene segments utilized by B-CLL cells and to what extent their characteristics resemble those of the H chain. We analyzed the V(L) and J(L)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Identifiers

PMID: 17380195
DOI: 10.2119/2006–00080.Ghiotto
PMCID: PMC1829199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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