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Article

Ig VH1 genes expressed in B cell chronic lymphocytic leukemia exhibit distinctive molecular features

1 Jan 1997

Abstract excerpt

Prior studies revealed that the leukemic B cells of patients with chronic lymphocytic leukemia (CLL) express a restricted Ig heavy chain variable region gene (VH gene) repertoire. However, this restriction needs to be re-evaluated in light of findings that the repertoire of Ig VH genes used by primary B cells of normal adults is actually more restricted than originally assumed. Because of this, we critically...

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PMID: 8977195
DOI: 10.4049/jimmunol.158.1.235

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Ig VH1 genes expressed in B cell chronic lymphocytic leukemia exhibit distinctive molecular featuresPMID 8977195Read ↗

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