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Article

Epigenetic events, remodelling enzymes and their relationship to chromatin organization in prostatic intraepithelial neoplasia and prostatic adenocarcinoma.

BJU international - 1 Apr 2007

Mohamed Mahmoud A, Greif Philipp A, Diamond James, Sharaf Osama, Maxwell Perry, Montironi Rodolfo, Young Robert A M, Hamilton Peter W

Abstract excerpt

OBJECTIVE: To explore the nuclear chromatin phenotype, overall epigenetic mechanisms, chromatin remodelling enzymes and their role as diagnostic biomarkers in prostate lesions, using high-resolution computerized quantitative digital image analysis (DIA). MATERIALS AND METHODS: A tissue microarray (TMA) was constructed using paraffin wax-embedded prostatic tissues from 78 patients, containing 30 cores of benign...

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Identifiers

PMID: 17378849
DOI: 10.1111/j.1464-410X.2006.06704.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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