Article
Changes in chromatin phenotype predict the response to hormonal deprivation therapy in patients with prostate cancer.
BJU international - 1 Feb 2009
Mohamed Mahmoud, Greif Philipp A, Diamond James, Sharafeldin Osama, Maxwell Perry, Montironi Rodolfo, O'Brien Aidan, Young Michael, Hamilton Peter W
Abstract excerpt
OBJECTIVE: To assess the value of studying chromatin organization using high-resolution digital image analysis to predict the response to hormonal-deprivation therapy (HDT) in patients with prostate cancer, using pretreatment prostate tissues. MATERIALS AND METHODS: A tissue microarray (TMA) was...
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