Article
Histone acetylation and chromatin pattern in cancer. A review.
Analytical and quantitative cytology and histology - 1 Feb 2007
Orr Jenny A, Hamilton Peter W
Abstract excerpt
Chromatin phenotype is known to be significantly disrupted in cancer. This has been demonstrated in many morphologic studies on cancer and in recent years by the application of digital texture analysis for quantitative evaluation of chromatin phenotype in neoplasia. Studies have consistently demonstrated the role of chromatin phenotype as a biomarker of diagnosis and prognosis. The underlying molecular mechanisms...
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