Article
Molecular biology of prostatic intraepithelial neoplasia.
The Prostate - 1 Aug 1996
Bostwick D G, Pacelli A, Lopez-Beltran A
Abstract excerpt
High-grade PIN is the most likely precursor of prostatic adenocarcinoma, according to virtually all available evidence to date. The clinical importance of recognizing PIN is based on its strong association with prostatic carcinoma. PIN has a high predictive value as a marker for adenocarcinoma. Its identification in biopsy specimens of the prostate warrants further search for concurrent invasive carcinoma. PIN is...
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