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DNA methylation biomarkers distinguishing early-stage prostate cancer from benign prostatic hyperplasia

5 Jan 2023

Abstract excerpt

Background: DNA methylation markers are considered robust diagnostic features in various cancer types, as epigenetic marks are commonly altered during cancer progression. Differentiation between benign prostatic hyperplasia (BPH) and early-stage prostate cancer (PCa) is clinically difficult, relying on the information of the patient's symptoms or levels of prostate-specific antigen. Methods: A total of 42 PCa...

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PMID: 37409096
DOI: 10.1016/j.prnil.2023.01.001

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