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Article

Abnormal DNA methylation, epigenetics, and prostate cancer

1 Jan 2007

Abstract excerpt

Human prostatic carcinogenesis is characterized by the accumulation of both genetic and epigenetic alterations. The epigenetic changes appear earlier and more consistently, and because the DNA sequence remains intact, may be therapeutically reversible. The mechanism(s) by which epigenetic changes appear during the pathogenesis of prostate cancer have not been established. Nonetheless, new methods for the...

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Share to Cancer-related gene regulation
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PMID: 17485372
DOI: 10.2741/2385

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