Article
Chromatin modifiers and carcinogenesis.
Trends in cell biology - 1 Dec 2004
Gregory Richard I, Shiekhattar Ramin
Abstract excerpt
Access of gene regulatory factors to the eukaryotic genome is modulated by chromatin. The organization of this nucleoprotein complex is highly dynamic and tightly regulated. The control of wide-ranging nuclear processes through the configuration of chromatin is achieved by the concerted actions of ATP-dependent chromatin-remodeling complexes and histone-modifying enzymes, and by the incorporation of specialized...
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