Article
Growth regulation of human variant histone genes and acetylation of the encoded proteins.
Molecular biology reports - 1 Jun 2000
Alvelo-Ceron D, Niu L, Collart D G
Abstract excerpt
The family of human histone genes consists of replication-dependent and independent subtypes. The replication-independent histone genes, also known as variants, give rise to distinct mRNAs, whose expression is regulated depending on the growth state of the cell, tissue type and developmental stage. In turn, the histone variants are differentially synthesized and modified by acetylation. Consequently, chromatin...
Topics
- Acetylation
- Amino Acid Sequence
- Chromatin
- Gene Expression Regulation, Developmental
- Genetic Variation
- Histones
- Humans
- Molecular Sequence Data
