Article
Histone acetylation as a therapeutic target.
Sub-cellular biochemistry - 1 Jan 2013
Selvi B Ruthrotha, Chatterjee Snehajyoti, Modak Rahul, Eswaramoorthy M, Kundu Tapas K
Abstract excerpt
The recent developments in the field of epigenetics have changed the way the covalent modifications were perceived from mere chemical tags to important biological recruiting platforms as well as decisive factors in the process of transcriptional regulation and gene expression. Over the years, the parallel investigations in the area of epigenetics and disease have also shown the significance of the epigenetic...
Topics
- Acetylation
- Animals
- Epigenesis, Genetic
- Gene Expression Regulation
- Genetic Predisposition to Disease
- Histone Deacetylase Inhibitors
- Histones
- Humans
- Phenotype
- Protein Processing, Post-Translational
- Signal Transduction