Article
Aberrant histone modification in endometriosis.
Frontiers in bioscience (Landmark edition) - 1 Jun 2014
Nasu Kaei, Kawano Yukie, Kai Kentaro, Aoyagi Yoko, Abe Wakana, Okamoto Mamiko, Narahara Hisashi
Abstract excerpt
Accumulating evidence suggests that epigenetic aberrations play definite roles in the pathogenesis of endometriosis. These include aberrations in genomic DNA methylation, microRNA expression, and histone modification. The aberrant histone modification status and the aberrant expression of histone deacetylases, which regulate histone acetylation, in endometriosis are the focus of this review. Herein, we summarize...
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