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Article

The Bxs6 locus of BXSB mice is sufficient for high-level expression of gp70 and the production of gp70 immune complexes.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2007

Rankin Joanna, Boyle Joseph J, Rose S Jane, Gabriel Luisa, Lewis Margarita, Thiruudaian Vasuky, Rogers Nicola J, Izui Shozo, Morley Bernard J

Abstract excerpt

High levels of the retroviral envelope protein gp70 and gp70 immune complexes have been linked to a single locus on chromosome 13 (Bxs6) in the BXSB model, to which linkage of nephritis was also seen. Congenic lines containing the BXSB Bxs6 interval on a non-autoimmune C57BL/10 background were bred in the presence or absence of the BXSB Y chromosome autoimmune accelerator gene (Yaa), which accelerates disease in...

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PMID: 17371996
DOI: 10.4049/jimmunol.178.7.4395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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