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Article

Genetic control of glycoprotein 70 autoantigen production and its influence on immune complex levels and nephritis in murine lupus.

Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 2000

Tucker R M, Vyse T J, Rozzo S, Roark C L, Izui S, Kotzin B L

Abstract excerpt

The F1 hybrids of New Zealand Black (NZB) and New Zealand White (NZW) mice spontaneously develop an autoimmune disease that serves as a model for human systemic lupus erythematosus. Autoimmunity in (NZB x NZW)F1 mice includes the production of autoantibodies to the endogenous retroviral envelope glycoprotein, gp70, and gp70-anti-gp70 immune complexes (gp70 IC) have been implicated in the development of lupus...

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Source

Identifiers

PMID: 10903778
DOI: 10.4049/jimmunol.165.3.1665

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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