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Article

A novel locus regulates both retroviral glycoprotein 70 and anti-glycoprotein 70 antibody production in New Zealand mice when crossed with BALB/c.

Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2004

Rigby Robert J, Rozzo Stephen J, Gill Herpreet, Fernandez-Hart Timothy, Morley Bernard J, Izui Shozo, Kotzin Brian L, Vyse Timothy J

Abstract excerpt

Lupus-prone New Zealand Black and New Zealand White mice produce high serum levels of the endogenous retroviral envelope protein gp70 and develop an Ab response to this autoantigen as part of their autoimmune disease. Linkage analysis of two crosses involving New Zealand and BALB/c mice mapped these traits to a group of overlapping loci, including a novel locus on proximal chromosome 12. This locus was linked...

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Identifiers

PMID: 15067091
DOI: 10.4049/jimmunol.172.8.5078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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