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Article

Function of the IL-2R for thymic and peripheral CD4+CD25+ Foxp3+ T regulatory cells.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2007

Bayer Allison L, Yu Aixin, Malek Thomas R

Abstract excerpt

IL-2 contributes to the production, function, and homeostasis of CD4+CD25+ T(reg) cells. However, it remains uncertain whether IL-2 is essential for the development of T(reg) cells in the thymus, their homeostasis in the periphery, or both. The present study was undertaken to investigate the contribution of IL-2 during thymic T(reg) cell development and its maintenance in peripheral immune tissue. Relying on...

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Identifiers

PMID: 17371960
DOI: 10.4049/jimmunol.178.7.4062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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