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Article

Burn injury reveals altered phenotype in mannan-binding lectin-deficient mice.

The Journal of investigative dermatology - 1 Jun 2007

Møller-Kristensen Mette, Hamblin Michael R, Thiel Steffen, Jensenius Jens Chr, Takahashi Kazue

Abstract excerpt

Burn injury destroys skin, the second largest innate immune organ in the body, and triggers chaotic immune and inflammatory responses. The pattern recognition molecule, mannan-binding lectin (MBL), plays an important role in the first-line host defense against infectious agents. MBL initiates the lectin complement pathway and acts as an opsonin. Recent studies suggest that MBL also modulates inflammatory...

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Identifiers

PMID: 17363917
DOI: 10.1038/sj.jid.5700748
PMCID: PMC2936508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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