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Article

Mannose-binding lectin-deficient mice display defective apoptotic cell clearance but no autoimmune phenotype.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2005

Stuart Lynda M, Takahashi Kazue, Shi Lei, Savill John, Ezekowitz R Alan B

Abstract excerpt

Mannose-binding lectin (MBL) is a circulating serum protein that is sequestered to sites of inflammation and infection. MBL is a member of the collectin family with structural similarities to the lung collectins and functional similarities to C1q. Both MBL and C1q activate complement; C1q activates the classical pathway and MBL the lectin pathway. Here we demonstrate that MBL binds apoptotic cells in vitro and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15749852
DOI: 10.4049/jimmunol.174.6.3220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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