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Article

Zebrafish curly up encodes a Pkd2 ortholog that restricts left-side-specific expression of southpaw.

Development (Cambridge, England) - 1 Apr 2007

Schottenfeld Jodi, Sullivan-Brown Jessica, Burdine Rebecca D

Abstract excerpt

The zebrafish mutation curly up (cup) affects the zebrafish ortholog of polycystic kidney disease 2, a gene that encodes the Ca(2+)-activated non-specific cation channel, Polycystin 2. We have characterized two alleles of cup, both of which display defects in organ positioning that resemble human...

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Identifiers

PMID: 17360770
DOI: 10.1242/dev.02827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17360770-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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