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Article

Cluap1 localizes preferentially to the base and tip of cilia and is required for ciliogenesis in the mouse embryo.

Developmental biology - 1 Sept 2013

Botilde Yanick, Yoshiba Satoko, Shinohara Kyosuke, Hasegawa Toshiaki, Nishimura Hiromi, Shiratori Hidetaka, Hamada Hiroshi

Abstract excerpt

Qilin is one of several genes in zebrafish whose mutation results in cystic kidney. We have now studied the role of its mouse ortholog, Cluap1, in embryonic development by generating Cluap1 knockout (Cluap1-/-) mice. Cluap1-/- embryos died mid-gestation manifesting impairment of ciliogenesis in various regions including the node and neural tube. The basal body was found to be properly docked to the apical...

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PMID: 23742838
DOI: 10.1016/j.ydbio.2013.05.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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