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Article

The Zic2 gene directs the formation and function of node cilia to control cardiac situs.

Genesis (New York, N.Y. : 2000) - 1 Jun 2014

Barratt Kristen S, Glanville-Jones Hannah C, Arkell Ruth M

Abstract excerpt

The first molecular herald of organ asymmetry during murine embryogenesis is found at the periphery of the node in early-somite stage embryos. Asymmetric gene expression and calcium accumulation at the node occurs in response to a left-ward flow of extracellular fluid across the node, generated b...

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Identifiers

PMID: 24585447
DOI: 10.1002/dvg.22767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24585447-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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