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Article

Transformation of murine pre-B-lymphocytes by v-erb-B: progression to growth factor independence and tumorigenicity.

Leukemia - 1 Jan 1992

Miller M, Kennewell A, Symonds G

Abstract excerpt

v-erb-B is the principal transforming gene of avian erythroblastosis virus, a replication defective retrovirus that transforms erythroid and fibroblast cells in vitro and causes erythroleukemia and fibrosarcoma in vivo. We have used a recombinant murine retrovirus, based on the truncated genome o...

Topics

Animals
B-Lymphocytes
Cell Division
Cell Transformation, Viral
Gene Expression Regulation, Leukemic
Gene Rearrangement, B-Lymphocyte, Heavy Chain
Genes, Viral
Macrophage Colony-Stimulating Factor
Mice
Mice, Inbred BALB C
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Neoplasm

Source

Identifiers

PMID: 1736010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1736010-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Transformation of murine pre-B-lymphocytes by v-erb-B: progression to growth factor independence and tumorigenicity.PMID 1736010Read ↗

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