Cell transformation by the epidermal growth factor receptor and v-erbB.

Article

Cell transformation by the epidermal growth factor receptor and v-erbB.

Cancer cells (Cold Spring Harbor, N.Y. : 1989) - 1 Aug 1991

Hayman M J, Enrietto P J

Abstract excerpt

It has become increasingly apparent that growth factor receptors can function as oncogenic proteins and play causal roles in cell transformation. A prime example is the epidermal growth factor receptor (EGFR), which belongs to the ligand-activated tyrosine kinase receptor family and is overexpres...

Topics

Animals
Cell Transformation, Neoplastic
ErbB Receptors
Humans
Mutation
Oncogene Proteins v-erbB
Oncogenes
Promoter Regions, Genetic
Retroviridae Proteins, Oncogenic
Transduction, Genetic

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