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Article

Notch2 is required for formation of the placental circulatory system, but not for cell-type specification in the developing mouse placenta.

Differentiation; research in biological diversity - 1 Mar 2007

Hamada Yoshio, Hiroe Takeshi, Suzuki Yuko, Oda Mayumi, Tsujimoto Yoshihide, Coleman John R, Tanaka Satoshi

Abstract excerpt

We have previously reported that a mutation in the ankyrin repeats of mouse Notch2 results in embryonic lethality by embryonic day 11.5 (E11.5), showing developmental retardation at E10.5. This indicated that Notch2 plays an essential role in postimplantation development in mice. Here, we demonst...

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Source

Identifiers

PMID: 17359302
DOI: 10.1111/j.1432-0436.2006.00137.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17359302-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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