Article

Impaired labyrinth formation prevents the establishment of the maternal-fetal interface in conditional Hand1-deficient mice

2020-09-03

Abstract excerpt

<h4>Introduction</h4> Congenital heart defects (CHD) affect approximately 1% of all live births, and often require complex surgeries at birth. Placental development and function is vital to ensure normal fetal development. We have previously demonstrated abnormal placental development and vascularization in human CHD placentas, and placental expression changes in genes important for heart development. Hand1 has r...

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Literature Corpus work: b1846fbb-6970-54ea-b154-75ea3ec60643
DOI: 10.1101/2020.09.02.280354

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