Article
Increase in GSK3beta gene copy number variation in bipolar disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2007
Lachman Herbert M, Pedrosa Erika, Petruolo Oriana A, Cockerham Melissa, Papolos Alexander, Novak Tomas, Papolos Demitri F, Stopkova Pavla
Abstract excerpt
The analysis of submicroscopic copy number variations (CNVs), also known as copy number polymorphisms (CNPs), is emerging as a new tool for understanding the genetic basis of cancer, developmental disorders, and complex traits. One area where this may be particularly useful is in the identification of genetic variants underlying schizophrenia (SZ) and bipolar disorder (BD). Linkage analysis and pharmacological...
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