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Article

Glycogen synthase kinase 3 beta gene structural variants as possible risk factors of bipolar depression.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2014

Ronai Zsolt, Kovacs-Nagy Reka, Szantai Eszter, Elek Zsuzsanna, Sasvari-Szekely Maria, Faludi Gabor, Benkovits Judit, Rethelyi Janos M, Szekely Anna

Abstract excerpt

The glycogen synthase kinase 3B (GSK3B) is an important target protein of several antidepressants, such as lithium, a mood stabilizer. Recent studies associated structural variations of the GSK3B gene to bipolar disorder (BP), although replications were not conclusive. Here we present data on copy number variations (CNVs) of the GSK3B gene probing the 9th exon region in 846 individuals (414 controls, 172 patients...

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Identifiers

PMID: 24677591
DOI: 10.1002/ajmg.b.32223
PMCID: PMC3980030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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