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Article

The GSK3B gene confers risk for both major depressive disorder and schizophrenia in the Han Chinese population.

Journal of affective disorders - 1 Oct 2015

Chen Jianhua, Wang Meng, Waheed Khan Raja Amjad, He Kuanjun, Wang Qingzhong, Li Zhiqiang, Shen Jiawei, Song Zhijian, Li Wenjin, Wen Zujia, Jiang Yiwen, Xu Yifeng, Shi Yongyong, Ji Weidong

Abstract excerpt

BACKGROUND: Glycogen synthease kinase-3B is a key gene encoding a protein kinase which is abundant in brain, and is involved in signal transduction cascades of neuronal cell development and energy metabolism. Previous researches proposed GSK3B as a potential region for schizophrenia. METHOD: To validate the susceptibility of GSK3B to major depressive disorder, and to investigate the overlapping risk conferred by...

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Identifiers

PMID: 26186530
DOI: 10.1016/j.jad.2015.06.040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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