Article
Lipid profile and inflammatory markers associated with estrogen receptor alpha PvuII and XbaI gene polymorphisms.
Translational research : the journal of laboratory and clinical medicine - 1 Jun 2009
Boroumand Mohammadali, Ghaedi Mahboubeh, Mohammadtaghvaei Narges, Pourgholi Leila, Anvari Maryam Sotoudeh, Davoodi Gholamreza, Amirzadegan Alireza, Saadat Soheil, Sheikhfathollahi Mahmood, Goodarzynejad Hamidreza
Abstract excerpt
Estrogen is established to influence lipoprotein metabolism and inflammatory markers. Alternations in estrogen receptor alpha (ESR1) expression and function may affect the role of estrogen in this regard. The aim of this study was to determine whether ESR1 PvuII and XbaI gene polymorphisms have effects on lipoprotein (a) as well as inflammatory variables in an Iranian population. Three hundred and ninety seven...
Topics
- Adult
- Aged
- Biomarkers
- Coronary Artery Disease
- Estrogen Receptor alpha
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
