Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effect of hormone replacement therapy on atherosclerotic severity in relation to ESR1 genotype in postmenopausal women.

Maturitas - 30 Jan 2003

Koivu Tommi A, Fan Yue-Mei, Mattila Kari M, Dastidar Prasun, Jokela Hannu, Nikkari Seppo T, Kunnas Tarja, Punnonen Reijo, Lehtimäki Terho

Abstract excerpt

OBJECTIVE: The atheroprotective action of estrogen is mediated by estrogen receptors (ESR) 1 and 2, expressed in atherosclerotic lesions. The effects of hormone replacement therapy (HRT) and ESR1 PvuII genotypes on atherosclerosis have not previously been studied prospectively in postmenopausal women. METHODS: We investigated the effect of HRT on the progression of atherosclerosis in a 5-year follow-up study of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Arteriosclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Follow-Up Studies

Share to Hormone Replacement Therapy

Share to Postmenopause

Share to Receptors, Estrogen

Share to Time Factors

Source

Identifiers

PMID: 12568733
DOI: 10.1016/s0378-5122(02)00293-1

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effect of hormone replacement therapy on atherosclerotic severity in relation to ESR1 genotype in postmenopausal women.PMID 12568733Read ↗

Effect of long-term hormone replacement therapy on atherosclerosis progression in postmenopausal women relates to functional apolipoprotein e genotype.Semantic proximity Read ↗

Effect of estrogen receptor-alpha (ESR1) gene polymorphism on high density lipoprotein levels in response to hormone replacement therapy.Semantic proximity Read ↗

The Association Between the rs2234693 and rs9340799 Estrogen Receptor α Gene Polymorphisms and Risk Factors for Cardiovascular Disease: A ReviewSemantic proximity Read ↗

Lipid, haemostatic and inflammatory variables in relation to the estrogen receptor alpha (ESR1) PvuII and XbaI gene polymorphisms.Semantic proximity Read ↗

Lipid profile and inflammatory markers associated with estrogen receptor alpha PvuII and XbaI gene polymorphisms.Semantic proximity Read ↗

Clinical Importance of Estrogen Receptor 1 (ESR1) Gene Polymorphisms and Their Expression Patterns in Coronary Artery Disease Patients: A Study from IndiaSemantic proximity Read ↗

Estrogen receptor alpha polymorphisms, estradiol level, and occurrence of atherosclerosis risk factors in healthy postmenopausal women.Semantic proximity Read ↗

Association of estrogen receptor {alpha} genotypes/ haplotypes with carotid intima-media thickness in Taiwanese women.Semantic proximity Read ↗

Genetic variation in estrogen receptor, C-reactive protein and fibrinogen does not predict the plasma levels of inflammation markers after longterm hormone replacement therapy.Semantic proximity Read ↗

Exonic, but not intronic polymorphisms of ESR1 gene might influence the hypolipemic effect of raloxifene.Semantic proximity Read ↗

Association between ESR1 and ESR2 gene polymorphisms and hyperlipidemia in Chinese Han postmenopausal women.Semantic proximity Read ↗

Vascular consequences of menopause and hormone therapy: importance of timing of treatment and type of estrogen.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.