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Article

CatSper gene expression in postnatal development of mouse testis and in subfertile men with deficient sperm motility

31 Dec 2003

Abstract excerpt

BACKGROUND: The search for Ca2+ channels residing in sperm has led to the recent cloning and characterization of a novel gene, named CatSper, which codes for a unique Ca2+ channel expressed exclusively in the testis. It plays an essential role in sperm motility, penetration into the oocyte, and ultimately in male fertility. In this study, we assessed the temporal profile of CatSper gene expression during mouse...

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PMID: 14688170
DOI: 10.1093/humrep/deh043

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