Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Efficient downregulation of alb1 gene using an AMA1-based episomal expression of RNAi construct in Aspergillus fumigatus.

FEMS microbiology letters - 1 May 2007

Khalaj Vahid, Eslami Hamid, Azizi Mohammad, Rovira-Graells Nuria, Bromley Mike

Abstract excerpt

An episomal RNAi silencing construct containing the inducible cbhB promoter and a hairpin structure has been made to downregulate the alb1 gene in the human pathogen Aspergillus fumigatus. Transformation of fungal protoplasts resulted in a high number of transformants with an inducible silenced phenotype (white spores). Efficient downregulation of the alb1 gene using this system suggests that this approach may...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspergillus fumigatus
Share to Down-Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Fungal

Share to Genes, Fungal

Share to Glucose

Share to Plasmids

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to RNA Interference

Source

Identifiers

PMID: 17343676
DOI: 10.1111/j.1574-6968.2007.00680.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Efficient downregulation of alb1 gene using an AMA1-based episomal expression of RNAi construct in Aspergillus fumigatus.PMID 17343676Read ↗

Gene silencing with RNA interference in the human pathogenic fungus Aspergillus fumigatus.Semantic proximity Read ↗

The developmentally regulated alb1 gene of Aspergillus fumigatus: its role in modulation of conidial morphology and virulence.Semantic proximity Read ↗

An autonomously replicating plasmid transforms Aspergillus nidulans at high frequency.Semantic proximity Read ↗

Regulated proteolysis of green fluorescent protein fusion proteins in <i>Aspergillus fumigatus</i>Semantic proximity Read ↗

RNA-mediated gene silencing in the phytopathogenic fungus Bipolaris oryzae.Semantic proximity Read ↗

RNA interference in Histoplasma capsulatum demonstrates a role for α‐(1,3)‐glucan in virulenceSemantic proximity Read ↗

Identification of a novel gene hbrB required for polarised growth in Aspergillus nidulans.Semantic proximity Read ↗

Antisense repression in Cryptococcus neoformans as a laboratory tool and potential antifungal strategySemantic proximity Read ↗

Hairpin-mediated down-regulation of the urea cycle enzyme argininosuccinate lyase in Agaricus bisporus.Semantic proximity Read ↗

Gene cluster involved in melanin biosynthesis of the filamentous fungus Alternaria alternata.Semantic proximity Read ↗

Characterization of an efficient gene cloning strategy for Aspergillus niger based on an autonomously replicating plasmid: cloning of the nicB gene of A. niger.Semantic proximity Read ↗

RNA-silencing in Penicillium chrysogenum and Acremonium chrysogenum: validation studies using beta-lactam genes expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.