Article
Gene cluster involved in melanin biosynthesis of the filamentous fungus Alternaria alternata.
Journal of bacteriology - 1 Jul 1993
Kimura N, Tsuge T
Abstract excerpt
The filamentous fungus Alternaria alternata produces melanin, a black pigment, from acetate via 1,8-dihydroxynaphthalene. To isolate a fungal gene required for melanin biosynthesis, we transformed an A. alternata Brm1- (light brown) mutant with the DNA of a wild-type strain genomic library constructed by use of a cosmid carrying the hygromycin B phosphotransferase gene. When hygromycin B-resistant transformants...
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