Article
The developmentally regulated alb1 gene of Aspergillus fumigatus: its role in modulation of conidial morphology and virulence.
Journal of bacteriology - 1 Jun 1998
Tsai H F, Chang Y C, Washburn R G, Wheeler M H, Kwon-Chung K J
Abstract excerpt
Aspergillus fumigatus, an important opportunistic pathogen which commonly affects neutropenic patients, produces conidia with a bluish-green color. We identified a gene, alb1, which is required for conidial pigmentation. The alb1 gene encodes a putative polyketide synthase, and disruption of alb1...
Topics
- Amino Acid Sequence
- Aspergillus fumigatus
- Base Sequence
- Cloning, Molecular
- Complement C3
- DNA, Fungal
- Gene Expression Regulation, Developmental
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Humans
- In Vitro Techniques
- Melanins
- Microscopy, Electron, Scanning
- Molecular Sequence Data