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Article

A demographic analysis of the fitness cost of extended longevity in Caenorhabditis elegans.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Feb 2007

Chen Jianjun, Senturk Damla, Wang Jane-Ling, Müller Hans-Georg, Carey James R, Caswell Hal, Caswell-Chen Edward P

Abstract excerpt

We monitored survival and reproduction of 1000 individuals of Caenorhabditis elegans wild type (N2) and 800 individuals of clk-1 and daf-2, and used biodemographic analysis to address fitness as the integrative consequence of the entire age-specific schedules of survival and reproduction. Relative to N2, the mutants clk-1 and daf-2 extended average life span by 27% and 111%, respectively, but reduced net...

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Identifiers

PMID: 17339638
DOI: 10.1093/gerona/62.2.126
PMCID: PMC2398707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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