Article
Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans.
Genetics - 1 Sept 1998
Gems D, Sutton A J, Sundermeyer M L, Albert P S, King K V, Edgley M L, Larsen P L, Riddle D L
Abstract excerpt
The nematode Caenorhabditis elegans responds to overcrowding and scarcity of food by arresting development as a dauer larva, a nonfeeding, long-lived, stress-resistant, alternative third-larval stage. Previous work has shown that mutations in the genes daf-2 (encoding a member of the insulin rece...
Topics
- Adaptation, Physiological
- Alleles
- Animals
- Base Sequence
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- DNA Primers
- Female
- Fertility
- Genes, Helminth
- Larva
- Male
- Mutation
- Phenotype
- Receptor, Insulin