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Article

Association of a functional polymorphism in the mu-opioid receptor gene with alcohol response and consumption in male rhesus macaques.

Archives of general psychiatry - 1 Mar 2007

Barr Christina S, Schwandt Melanie, Lindell Stephen G, Chen Scott A, Goldman David, Suomi Stephen J, Higley J Dee, Heilig Markus

Abstract excerpt

CONTEXT: Innate differences in opioid neurotransmission are hypothesized to influence abuse liability of alcohol. In humans, a variant of the mu-opioid receptor gene (OPRM1A118G) increases receptor affinity, alcohol-induced euphoria, and risk for alcohol use disorders. OBJECTIVE: To determine whe...

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Source

Identifiers

PMID: 17339526
DOI: 10.1001/archpsyc.64.3.369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17339526-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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