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Article

The potential effect of gender in combination with common genetic polymorphisms of drug-metabolizing enzymes on the risk of developing acute leukemia.

Haematologica - 1 Mar 2007

Bolufer Pascual, Collado Maria, Barragán Eva, Cervera José, Calasanz María-José, Colomer Dolors, Roman-Gómez José, Sanz Miguel A

Abstract excerpt

BACKGROUND AND OBJECTIVES: We examined common polymorphisms in the genes for glutathione S-transferase (GST), cytochrome P450 (CYP), quinone oxoreductase (NQO1), methylene tetrahydrofolate reductase (MTHFR), and thymidylate synthetase (TYMS) and the role of gender associated with the susceptibility to de novo acute leukemia (AL). DESIGN AND METHODS: We conducted a case-control study analyzing the prevalence of...

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Share to Leukemia, Myeloid

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Source

Identifiers

PMID: 17339179
DOI: 10.3324/haematol.10752

Genes

NQO1
GSTT1
MTHFR
TYMS
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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