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Article

Polymorphisms of CYP1A1 and glutathione S-transferase and susceptibility to adult acute myeloid leukemia.

Haematologica - 1 Jun 2004

D'Alò Francesco, Voso Maria Teresa, Guidi Francesco, Massini Giuseppina, Scardocci Alessandra, Sica Simona, Pagano Livio, Hohaus Stefan, Leone Giuseppe

Abstract excerpt

BACKGROUND AND OBJECTIVES: The origin of acute myeloid leukemia (AML) may be explained by a combination of genetic susceptibility factors and environmental exposure. We studied the polymorphisms of cytochrome P450 CYP1A1 and glutathione S-transferase (GST), enzymes involved in the metabolism of carcinogens and anti-cancer drugs, as risk factors for adult AML. DESIGN AND METHODS: The prevalence of CYP1A1*2A, *2B...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15194533

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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