Article
High prevalence of the CCR5Delta32 HIV-resistance mutation among Estonian HIV type 1-infected individuals.
AIDS research and human retroviruses - 1 Feb 2007
Adojaan Maarja, Mölder Tarmo, Männik Andres, Kivisild Toomas, Villems Richard, Krispin Tõnu, Ustav Mart
Abstract excerpt
The aim of this survey was to investigate human immunodeficiency virus type 1 (HIV-1) coreceptor, chemokine receptor 5 (CCR5), polymorphism among Estonian HIV-1-infected individuals. Homozygous CCR5Delta32 genotypes have been associated with resistance to HIV-1 infection; however, inconsistent evidence exists as to whether a single copy of a mutant allele among heterozygotes confers protection from HIV-1...
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