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Article

Prevalence of the CCR5Delta32 mutation in Brazilian populations and cell susceptibility to HIV-1 infection.

Human genetics - 1 Jul 2002

Grimaldi Rogério, Shindo Nice, Acosta Angelina Xavier, Dourado Inês, Brites Carlos, de Melo Carvalho Ozenilda, Brito Ivo, Bou-Habib Dumith Chequer, Galvão-Castro Bernardo

Abstract excerpt

We investigated the occurrence of the CCR5Delta32 mutation in various regional ethnic groups in Brazil and tested the resistance of mutant peripheral blood mononuclear cells (PBMCs) to infection by HIV-1 in vitro. The heterozygous prevalence was 5.3% in uninfected African descendents and 8.8% in HIV-1-positive individuals (neither population had Delta32/Delta32). German descendents were 11% heterozygous and l%...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12136242
DOI: 10.1007/s00439-002-0747-x

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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