Article
Molecular characterization of the CCR 5 gene in seronegative individuals exposed to human immunodeficiency virus (HIV).
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jan 2002
Rugeles M T, Solano F, Díaz F J, Bedoya V I, Patiño P J
Abstract excerpt
BACKGROUND: Both clinical and laboratory evidence in exposed seronegative (ESN) individuals to human HIV-1 has suggested the existence of mechanisms of natural resistance to the infection. A 32 base-pair deletion in the gene that codes for the CCR5, which is the main coreceptor for HIV-1, confers a high degree of resistance to HIV-1 infection. However, the genotype Delta32/Delta32 is present only in 2-4% of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
